A Sticky Business

Apoptosis: A sticky business

Many proteins that resemble Bcl-2 or bind to it have been found using techniques that reflect interactions in vitro or depend on DNA homology, but we still do not know how this master regulator of apoptosis works.

9008 Sticky Prices , Money , and Business Fluctuations

Can nominal contracts create monetary nonneutrality if they arise endogenously in general equilibrium? Yes, if (1) agents have complete information about the money stock and (2) shocks to the system are purely redistributive and private information, precluding conventional insurance markets. Without contracts, money is neutral toward aggregate quantities. However, risk-sharing between suppliers...

The sticky business of discovering cadherins

JCB • VOLUME 170 • NUMBER 4 • 2005 514 The sticky business of discovering cadherins hen scientists move from one lab to another, the inevitable change in reagents or mysterious new water properties can vex even the most robust of experimental set-ups. But for Masatoshi Takeichi, a change in the recipe for a trypsin solution when he moved from Kyoto University to the Carnegie Institution Departm...

Mechanical Heart Valves in Pregnancy: A Sticky Business.

Sticky Business Orchestrating Cellular Signals at Adherens Junctions

Cohesive sheets of epithelial cells are a fundamental feature of multicellular organisms and are largely a product of the varied functions of adherens junctions. These junctions and their cytoskeletal associations contribute heavily to the distinct shapes, polarity, spatially oriented mitotic spindle planes, and cellular movements of developing tissues. Deciphering the underlying mechanisms tha...